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Symbol Name ID |
Lrba
LPS-responsive beige-like anchor MGI:1933162 |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased circulating IgA level |
Decreased circulating IgG level |
Decreased circulating total IgM |
Decreased specific antibody response to vaccination |
Pancytopenia |
Autoimmune hemolytic anemia |
Chronic neutropenia |
Decreased proportion of class-switched memory B cells |
B lymphocytopenia |
Thrombocytopenia |
Autoimmune thrombocytopenia |
Lymphoma |
Lymphoproliferative disorder |
Splenomegaly |
| Disease(s) Associated with LRBA | ||||||||||||||
| common variable immunodeficiency 8 |
| Mouse Phenotypes | increased regulatory T cell number |
increased myeloid cell number |
abnormal NK cell physiology |
impaired natural killer cell mediated cytotoxicity |
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| Availability | Mouse Genotype | ||||
| LrbaGt(OST69142)Lex/LrbaGt(OST69142)Lex | |||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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